Wednesday, October 30, 2019

Intellectual property project ( Business and Commercial law ) Assignment

Intellectual property project ( Business and Commercial law ) - Assignment Example This paper presents an example of a case in which the intellectual property legislation of the cell phone market has been breached. In the shop where I spotted this original HTC phone, it was selling at $120. However, according to what one of the shop attendants told me, the price was slightly negotiable. I guess it could sell as low as $110. The price of this product according to the shop, in which I spotted it, was $52. Comparing with the previous similar phone (real) that I had seen earlier, I got interested in why it was selling so cheap. At a glance, I could not notice any difference. However, after a close look at the phone, I noticed some differences from the original phone. The original HTC phones are manufactured by a company called HTC Corporation, with its headquarters in Xindian, New Taipei City, Taiwan. The company was formerly known as High-Tech Computer Corporation. State laws protect the intellectual properties. Any attempt use an intellectual property without authorization is considered infringement (Hg.org, 2015). The manufacturers of the fake hTC mobile phones violate the intellectual laws in a number of ways. The first and foremost, their product resembles the HTC corporation’s product by general look as well as the product name. The HTC label used on the phone is a trademark of HTC Corporation. Any other firm that sells products with a similar label violates the federal law No. 8 of 2002, as provided by the trade regulations in UAE. If the firm runs its businesses in United States, it would be a violation of the intellectual law, as provided in section 396(3A) of Act 1988 (Groves, 1997). The production of a product similar to those patented by another company is an offense. It violates the intellectual laws related to copyright, patent, design rights, just to mention a few. The manufacturer of the fake HTC mobile, in this case, violated the intellectual laws by manufacturing phone similar to the ones that existed

Monday, October 28, 2019

Globalisation and HRM

Globalisation and HRM This assignment discusses on the link between globalisation and HRM. It explains how HRM practices like recruitment and selection should be carried out in order to improve organisation performance and enhance important corporate aspects like how to dominate the global market. Human Resource Management is act of dealing with people in an organisation how to manage their behaviour and activities to increase profits. According to Decenzo and Robbins, (2004), and Bernardin, (2003), Human resources management (HRM) is the function within an organisation that focuses on recruitment of management and providing directions for the people who work in the organisation. Human resources management can also be performed by line manager and deals with issues related to people such as performance management, hiring, wellness, benefit safety, compensation, training and communication. In addition, HRM is the sense of getting things or work done through people. Its an essential part of every managers responsibilities, but many organisations find it advantageous to establish a specialist division to provide an expert service dedicated to ensuring that the human resource function is performed efficiently. Also how HRM processes should be in order to cope with global issues. The effect of globalisation on recruitment and selection is seen clearly now that organisations need to recruit people that are able to work in global situations and contribute to the global environment. According to Castells M, (2000), Globalisation is an inevitable phenomenon in human history that has been bringing the world closer through the exchange of products, information, goods, culture, services and knowledge. Over the last decades the pace of this global integration has become much faster and dramatic because of unprecedented advancements in science, communication, transport, technology and firms. So HR managers should understand how to cope with all these changes especially as many people prefer to get high quality products if they are offered from abroad. If companies understand this, they will reach organisational goals effectively. Saiyadain M (2004) According to Globalisation has contributed to various competencies which organisations have found effective to improving profit. Other positive aspects include financial organisation situations; where the developing counties have benefited from developed countries and financial organisations such as IMF (International Monetary Fund) and WTO (World Trade Organisation), where by these organisations invest money or commerce loans to the financial organisation. Also, globalisation has created thousands of jobs around the world and also has contributed to the growth of the worlds economy. In other contribution, globalisation has been effective to providing access to technological improvements and has also led to the reduction of barriers to trade. A market is what a business targets to benefit from by satisfying consumer needs. According to S. Skinner, (1998), a market is a social arrangement that allows buyers and sellers to discover information and carry out voluntary exchange of goods and services. Its one of the two key institutions that organize trade, along with the right to own property. Its importance to globalisation is to make the producer know what consumers of the market need at the moment in terms of satisfaction and organisation practices. Globalisation has made organisations to participate in local and international markets to improve quality of trade and the level of business operations. HRM needs to work on practical matters that affect their business because they need to cope with everyday changes and balance internal and external issues. There are issues over importance of communication or culture. These include issues about the rate of importance between background culture and adopted culture. However, it sometimes depends on the situation of the company. Contribution of the employee depends on the environment he or she is in. In case employing someone from a less developed country, training would be right measure for improvement. However, if he person is from a more developed region, then the HR department may want to just tech the person how to cope with the environment and the individual will be able to participate fully in everyday business. Capon C, (2004), Capon C, (2004), states that Development of global telecommunication infrastructures has led to success in establishing stable communication through service such as cell phones, internets, and satellites in the developing countries such Kenya, Uganda and Somalia. This has provided a link of third world countries to developed nations thus reducing world poverty. This point shows how important HRM is to the world, as recruiting the right person to telecommute can change the world. Globalisation has made trade liberalization; whereby every one can gain the movement to lower trade barriers and to open the world trade. It has increased the growth of goods and services, where people have got more income to improve the living standard in the society. Foreign competition is increasingly extending beyond the goods firms. Outsourcing of services in dorks, such as call centers. Its important to the business due to less cost. but is it morally acceptable by your customers. It improves cultural awareness between organisations, where it brings employees of different background of culture to work together without any conflict in the working environment. Saiyadain M (2004 Even though there are positive aspects, there are also negative issues that globalisation can cause. These include; Environmental pollution increases with globalisation as countries manufacture more products to satisfy demand. Also there is increase of carbon emissions to the atmosphere, whereby people are always traveling from one place to another, for example when and individual is assigned to work globally, he or she will have to travel by air thus contribute to air pollution. HR managers should act responsible and protect the environment. This could be done by limiting the number of trips carried out by the employees if possible, and also using transport means which are more environmental friendly. Capon C, (2004), Globalisation encourages development in already developed countries therefore leaving less developed countries to become poorer. Recruitment is the process of identifying that the organisation or company requires employing someone to the point at which application forms for the post have arrived at the company. According to Saiyadain, (2004), recruitment is the process where the organization gets people to work for them so as to be part of the organisation functions. A successful recruitment depends upon finding the right people with the necessary skills, knowledge, experience and qualifications to do the work required together with the ability to make a positive contribution to the values and aims of the company or organisation. Mendenhall M, (2007), Selection then consists of the processes involved in choosing from applicants, suitable or the right person to fill the post needed in the organisation with the right qualification. The selection process needs to be well carried out because HR managers may choose the wrong people and leave the right people. Matthewss J et al, (2004), states that, recruiting people who are wrong for the for the organisation can lead to increased labour turnover, increased costs for the organisation and lowering of morale in the existing workforce. Such workers are likely to be discontented, unlikely to give of their best and end up leaving voluntarily or involuntarily when their unsuitability becomes evident. They will not offer the flexibility and commitment that many companies seek. Managers and supervisors will have to spend extra time on further recruitment exercises, when is needed in the first place is a systematic process to assess the role to be filled and the type of skills and abilities needed to fill it. Most recruitment systems will be simple with stages that can be followed as a routine whenever there is a vacancy to be filled and which can be monitored and adapted in the light of experience. According to Dessler, (2005), The organisation should be aware that the provision of the disability discrimination Act 1995 not only makes it unlawful to discriminate against disabled individuals without justifiable reason but also require employers to make reasonable adjustments to the workplace arrangements. Brewster C et al, (2007) states that The employer has the legal responsibility to ensure that no unlawful discrimination occurs in the recruitment and selection process on the groups of race, age and religion. Equality of opportunity is an integral part of the recruitment and section process, and to these end employers may offer encouragement and training to any under represented group of workers. For example to the management development of woman who are under- presented in management grades. The world in which human resource managers exist and with which they interact is continually changing, generating new issues and challenges for HR managers to consider during recruitment. There are specific qualities that managers should look at when recruiting for specific functions in the organisation. With the increase in intensified competition among organisations in aspects of performance, productivity and competent expertise, HRM managers are faced with a challenge of recruiting professional staff to have a competitive advantage in the market. According to Porter M (1998) Competitive advantage is an advantages ove competitors gained by offering cunsumers greater value, either by means of lower prices or by providing greater benefits and services that justifies higher prices Although recruitment has always held an important place within organisations the growing demand for highly skilled staff has meant that effective recruitment practices are now becoming a considerable resource of competitive advantages used to improve performance. This recruitment and selection learning module is designed to prepare individuals and trainers to introduce effective recruitment and selection systems. In addition the learning pack clearly outlines how to introduce a supporting measurement system for the recruitment process to maximize both individuals and organisations efficiency. Capon C, (2004), states that, With the increased pace in globalization, organisations are now operating under a multicultural environment. Hence organisations face a challenge of recruiting knowledgeable, talented, and skilled employees from different background as they are able to manage internationally. Multicultural environments boost business performance since there are different views from participants. Capon C, (2004), states that, Moreover, the riding wave of technological innovation forces the HRM managers to recruit staff who posses the acquired knowledge need to operate new machinery, equipment which are equipped with the new knowledge E.g. the use of email and internet as tools of information provision and communication, the use of computer databases to hold staff information and generate reports. Pareek U, (2004), states that, Furthermore, with global standardization of policies practices and HRM philosophies, the HR needs to diversify their strategies. Also organizations need to react in a way that is satisfactory to both the employees and consumers. For example, HR manager should emphasize on employing people who know proper hygiene when preparing food for the customers, in three years ago MacDonalds food chain received complaints from his customer that the food prepared was not good for the health of people, whereby their food contained a lot of fat and other unhealthy contents. Thus individuals who used to be loyal customers had a risk of becoming obese. At the same time, workers left their work due to the complaints from customers. MacDonalds therefore lost a lot of customers in a certain point as before, but after sometime, they changed the way of preparing their food and how they offer their services, then the number of customers also increased much more than the previ ous. According to Bernardin, (2003) Meeting the expectations of the law, the employer has the legal responsibility to ensure that no unlawful discrimination occurs in the recruitment and selection process on the grounds of sex, race, disability, sexual orientation, age and religion. Equality of opportunity, its an integral part of the recruitment and selection process and to this end employers may offer training and encouragement to any under represented groups. Brewster C et al, (2007) states that, Employees and their representatives will also have an interest in fair, non discriminatory recruitment and selection policies, and they should be fully consulted when new procedures are introduced or existing procedures reviewed. The sex discrimination Act 1975, the race relation Act 1976 and 2000, the employment equality regulations and the disability discrimination ACT 1995 set out the legal requirements for employers. Capon C, (2004), States that, The organisations should be aware that the provisions of the disability discrimination Act 1995 not only make it unlawful to discriminate against disabled individuals without justifiable reason but also require employers to make reasonable adjustments to the workplace or working arrangements. Detailed guidance is available in the code of practice on the elimination of discrimination in employment. Robert et al (2004), and Dessler, (2005), Some of the issues which make the link between HRM and Globalisation more intensified include the rate at which the HR manager responds to Global-economic activities. For example if there is an absolute market in a different country, the HR department is responsible for defining means of which the business will perform in order to capture the market, including recruiting the right people for the job, and training them for them to learn how to develop. Pareek U, (2004), In conclusion, responding to intensified competition is crucial for an organisation since without competition its difficult to progress and offer excellent services. As a HR manager, understanding this concept will help the manager in defining exactly what the organisation prefers in terms of who to employ, and as a result, the right people will be employed for the job thus generate profit. In addition, the profit will even be high since the global economy has offered more market share to businesses. Reference Capon C, (2004), understanding organisational context 2nd Edition, Pearson education limited England. Brewster C et al, (2007) international human resource management, 2nd chartered institute of personnel and development, London. Pareek U, (2004), designing and managing human resource systems 3rd edition, Vijay Primlani, New Delhi. Mendenhall M, (2007), international human resource management, 4th Edition, Routledge, London. Matthewss J et al, (2004), human resource development 3rd edition Kogan page, New Delhi Decenzo, D and Robbins, S (2004), Personnel/Human Resource Management, Third Edition, Prentice Hall Inc, New Delhi. S. Skinner, (1998), Marketing, Houghton Mifflin, USA Bernardin J, (2003), Human Resource Management, Third Edition, Tata McGraw- Hall, New Delhi Robert C, et al (2004), Managing Human Resource, Third Edition, Pearson Education Inc, New Delhi Dessler G, (2005),Human Resource Management, Ninth Edition, Pearson Education, New Delhi Porter, M, (1998), Competitive Strategy, Free Press, USA Saiyadain M (2004), Human Resources Management, Third Edition, Tata McGraw- Hall, New Delhi

Friday, October 25, 2019

Japanese Business Etiquette Essay -- Japan Traditions Culture Business

Japanese Business Etiquette Content: I.  Ã‚  Ã‚  Ã‚  Ã‚  Introduction II.  Ã‚  Ã‚  Ã‚  Ã‚  History a.  Ã‚  Ã‚  Ã‚  Ã‚  What is the country ¡Ã‚ ¦s political tradition? b.  Ã‚  Ã‚  Ã‚  Ã‚  Is there a dictatorship or other form of the government which means that the government will be closely involved in your efforts? c.  Ã‚  Ã‚  Ã‚  Ã‚  Is there a history of colonization or occupation by another state? d.  Ã‚  Ã‚  Ã‚  Ã‚  Are there any tensions with neighbors? e.  Ã‚  Ã‚  Ã‚  Ã‚  Is the country secular or not? f.  Ã‚  Ã‚  Ã‚  Ã‚  Religion? III.  Ã‚  Ã‚  Ã‚  Ã‚  Concepts for doing business a.  Ã‚  Ã‚  Ã‚  Ã‚  How does this culture see time? b.  Ã‚  Ã‚  Ã‚  Ã‚  How does this culture gather information? c.  Ã‚  Ã‚  Ã‚  Ã‚  How does this culture fit into the other models presented in class? d.  Ã‚  Ã‚  Ã‚  Ã‚  What are the important values in this culture; is there understanding of these values the same as yours? e.  Ã‚  Ã‚  Ã‚  Ã‚  How do hierarchies and negotiation styles fit in? f.  Ã‚  Ã‚  Ã‚  Ã‚  Is bribery an issue? IV.  Ã‚  Ã‚  Ã‚  Ã‚  Social Situation a.  Ã‚  Ã‚  Ã‚  Ã‚  Are there any particular manners or etiquette tips that are very important? b.  Ã‚  Ã‚  Ã‚  Ã‚  Is there a place for humor, small talk, etc.? c.  Ã‚  Ã‚  Ã‚  Ã‚  Are there particularities about food and drink? d.  Ã‚  Ã‚  Ã‚  Ã‚  Are there particularities about dress, body contact? V.  Ã‚  Ã‚  Ã‚  Ã‚  Conclusion VI.  Ã‚  Ã‚  Ã‚  Ã‚  References a.  Ã‚  Ã‚  Ã‚  Ã‚  History b.  Ã‚  Ã‚  Ã‚  Ã‚  Concepts for doing business c.  Ã‚  Ã‚  Ã‚  Ã‚  Social situations I. Introduction Our German company is planning a joint venture in Japan. For the reason that this is the first international venture of the company in its thirty year reason, we will send you, a delegation of men and women from our company, for a week-long trip to Japan for a first meeting with our counterparts. There are several factors which we tried to cover while for you in order to make your stay as successful as possible: „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  history „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  what factors might pose problems for Germans „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  how Germans can avoid offending the locals „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  how Germans can avoid culture shock „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  critical points to remember for the initial meetings We tried to collect all these information in order to smooth your way in the Japanese business world. We hope that this report will help you to find the way through the new culture you will soon have to handle. II. History a.  Ã‚  Ã‚  Ã‚  Ã‚  What is the country ¡Ã‚ ¦s political tradition? Japan is academically considered a constitutional monarchy with a bicameral parliament, the Kokkai or Diet. A constitutional monarchy is a form of government which represents a compromise between tho... ...r for the initial meetings Hopefully, we could contribute to your upcoming business relationship and could help you answering all your questions and help to take away your anxiety. Even though we know that Japanese culture totally differs from our German culture, we have faith in you. We think that you will smooth our way for upcoming transactions and relationships. V. References a.  Ã‚  Ã‚  Ã‚  Ã‚  History „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  www.japan-guide.html „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  www.fact-index.com „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  www.mapzones.com „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  www.dal.ca „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  http://www.nationmaster.com/encyclopedia/Foreign-relations-of-Japan „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  http://www.nationmaster.com/encyclopedia/History-of-Japan „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  www.japan-tipp.de „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  www.oldbookroom.com b.  Ã‚  Ã‚  Ã‚  Ã‚  Concepts for doing business „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  http://www.venturejapan.com/japan-business-culture-meeting.htm „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  http://www.rieti.go.jp/en/rieti_report/012.html, „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  www.kellogg.northwestern.edu c.  Ã‚  Ã‚  Ã‚  Ã‚  Social situations „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  http://www.geocities.com/japanfaq/FAQ-Manners.html „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  http://gojapan.about.com/cs/etiquetteinjapan/a/bowing.htm „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  http://www.cyborlink.com/besite/japan.htm „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  http://www.escapeartist.com/efam27/japan.html „ «Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  http://www.japan-guide.com

Thursday, October 24, 2019

Oniomania: Psychology and Higher Income Levels Essay

This condition generally interferes with the functioning of an individual where an individual is faced with an overwhelming urge to shop. Signs include; someone being overly preoccupied with shopping (shop till you drop), excessive shopping of especially items that are not used, which eventually leads to debts, marital problems with the spouse, or even other family members such as parents. Other signs include; thinking excessively about money, feeling a rush of euphoria and anxiety when shopping, and ultimately lying about purchases made.(Krueger 1988) How it starts Oniomania has no direct cause, since there is no specific pattern to the way of life of the people who have been diagnosed with as being shopoholics. Some Psychologists speculate that this condition might generate from developmental neurobiological and cultural influences, thus early life influences such as sexual abuse might be some of the cause. It should also be noted that this condition is mostly common in the developed world, probably because of higher income levels thus more of the disposable income and a higher ease of access to credit facilities. Oniomania is also higher in women as compared to men, with a survey in the USA revealing that of those people that were diagnosed with the condition 80% were women.(Lawrence 1990) Advantages The biggest beneficiaries of shopopholism are the retailers who benefit with increased sales especially during the festive seasons. Shopoholics on the other hand benefit to some extent by having a wide variety of items that they bought to choose. They also feel elated in the experience of shopping and hide from the problems in their lives, and some even feel more gratified than even being in a relationship. It should be noted however that these benefits ultimately lead to bigger problems. Disadvantages Advantages include; financial loss, incurring huge debts, family breakdown, loss of friendships and poor work performance caused by loss of time. One can also revamp into theft and psychological trauma. How to stop it Compulsive spending may come with a host of other disorders, which include; alcoholism and eating disorder. It is important for someone who bears the symptoms to seek counseling. Works cited Roberts JA, Tanner JF Jr. Compulsive buying and sexual attitudes, intentions, and activity among adolescents: an extension of Roberts and Tanner (2000). Aboujaoude E, Gamel N, Koran LM. A 1-year naturalistic following of patients with compulsive shopping disorder. J Clin Psychiatry. 2003

Wednesday, October 23, 2019

Character Sketch of Mr.Woodwark from Finnie Walsh

Even in his most upset moments,Mr.. Woodward is an unfailing attractive character in the novel â€Å"Finnier Walsh†,written by Steven Galloway. Mr.. Woodward first impressed me when he met Finnier after that unfortunate accident for the first time. He starts the conversation with ‘Why aren't you boys playing hockey today? † instead of blaming them or cutting down their arms. That is not easy for him to forgive. But he still made it. Maybe because Finis's sparkling and teasing wit bring Mrs.. Woodward disapproval and Mr.. Woodward's attention. Mr..Woodward is always a great listener and glad to hare his own suggestions. I think, since then, some connections have already had between Mr.. Woodward and Finnier. After Mr.. Woodwork lost his hands, he began to relieve the burden of guilty of Finnier. He even says some tolerant word like â€Å"l knew our driveway is a fine place to play, so if you want play, then go ahead. † and â€Å"hold this, you will feel much better. † Because of his exceptional powers of observation, as well as his good sense, he lets Finnier released from the huge guilty and even becomes his support.As Finis's saying at the third period, ‘Your dad is the reason I come a goalie. † Mr.. Woodward sometimes misjudges things because of staying stubbornly. However, he has not realized his unique verve. Mr.. Woodward becomes more sensitive after that accident. For example, he cares about the way people treat him, and wonders that whether he is treated Just like the other ordinary people or not. He insists that â€Å"People work for what they get and do not accept charity. † Mr.. Woodward Is a strong man. He doesn't want people find that he feels upset without his arm.He refused any kind of compassion, so he lives as If he leaves his arm in a washroom or somewhere else. HIS confidence, a combination of stubborn and strengthen, leads him Into small mirrors and also keeps him alive. Unlike Pal, the man he works with, who keeps losing his claw for about twenty years and never give up to get new one, Mr.. Woodward Just accept It and moves on quickly. It seems like that he never fight with his fate, which Is realistic. He spends most of his time on education with wholehearted enthusiasm. As I said, Mr.. Woodward Is a strong man who always has his way to release.For me,Mr.. Woodward Is the most extinguished and unique character In this book. Although he was not mentioned a lot,he Is still Impressive,as well as attractive. He Just sets up a good example for Paul and Flannel,also for us. Character Sketch of Mr.. Woodward from Finnier Walsh By actually]nice becomes his support. As Finis's saying at the third period, norm dad is the reason I Mr.. Woodward is a strong man. He doesn't want people find that he feels upset without his arm. He refused any kind of compassion, so he lives as if he leaves his arm in a washroom or somewhere else.His confidence, a combination of stubborn ND strengt hen, leads him into small mirrors and also keeps him alive. Unlike Pal, the up to get a new one, Mr.. Woodward Just accept it and moves on quickly. It seems like that he never fight with his fate, which is realistic. He spends most of his time on education with wholehearted enthusiasm. As I said, Mr.. Woodward is a strong man For me,Mr.. Woodward is the most distinguished and unique character in this book. Although he was not mentioned a lot,he is still impressive,as well as attractive. He Just sets up a good example for Paul and Finnier,also for us.

Tuesday, October 22, 2019

Willis Johnson and the Egg Beater Invention

Willis Johnson and the Egg Beater Invention African-American Willis Johnson of Cincinnati,  Ohio, patented and improved the mechanical egg beater (U.S. pat# 292,821) on February 5, 1884. The beater was made up of a handle attached to a series of spring-like whisk wires used to help mix ingredients. Prior to his eggbeater, all mixing of ingredients was done by hand and was quite labor-intensive and time-consuming. In fact, what Willis Johnson had really invented was the early mixing machine and not just an egg beater. His device was not intended for eggs alone. Johnson had designed his egg beater and mixer for eggs, batter, and other bakers ingredients. It was a double-acting machine with two chambers. Batter could be beaten in one section and eggs could be beaten in another section, or one section could be cleaned while the other section could continue beating. Egg Beater Patent Abstract The object of [the] invention is to provide a machine wherewith eggs,  batter, and other similar ingredients used by bakers, confectioners, c., can be beaten or mixed in the most intimate and expeditious manner. The machine consists, essentially, of  a mainframe within which is journaled a driving-wheel and a pinion or pulley, the horizontal shaft of the latter having at its opposite ends clutches or sockets, with which are engages square or other non-circular arbors at the inner extremities of a pair of beater shafts. These shafts, which are armed with suitable blades, beaters, or stirrers, are journaled in cylinders that occupy detachable trays or racks applied to the opposite sides of the main frame,  hooks, and staples or the convenient devices being employed for retaining said racks in their proper places. As a result of this construction, either one or the other of both cylinders can be readily applied to the racks, and the latter can be coupled to the machine, so as to e nsure  a very rapid revolution is applied to the driving-wheel, as hereinafter more fully described. Other Types of Mixers Stand mixers mount the motor in a frame or stand which bears the weight of the device. Stand mixers are larger and have more powerful motors than hand-held mixers. A special bowl locks into place while the mixer runs.  Heavy-duty commercial versions can have bowl capacities greater than 25  gallons and weigh thousands of pounds. Mixers that are 5 gallons or less are usually countertop mixers, while larger mixers tend to be floor models due to their size and weight.Spiral mixers  are specialist tools for mixing dough. A spiral-shaped agitator remains stationary while the bowl rotates. This method enables spiral mixers to mix the same size dough batch much quicker and with less under-mixed dough than a similarly powered planetary mixer. This allows the dough to be mixed without increasing its temperature, ensuring the dough can rise properly.Planetary mixers  consist of a bowl and an agitator. The bowl remains still while the agitator rapidly moves around the bowl for mixing. W ith the ability to mix a wide variety of ingredients, planetary mixers are more versatile than their spiral counterparts. They can be used to whip and blend.

Monday, October 21, 2019

Adult Development and Collaborative Learning

Adult Development and Collaborative Learning Introduction Theories of collaborative learning have, for a number of years, lend credence on the manner in which learners operate within a group setting. Several empirical studies have been carried out to explore the role of collaborative learning in adult development (Dillenbourg et al., 1996, p. 1). According to Kiely, Sandmann and Truluck (2004), the number of adults enrolled for various degree programs has increase remarkably in the last three decades (p. 17).Advertising We will write a custom assessment sample on Adult Development and Collaborative Learning specifically for you for only $16.05 $11/page Learn More For instance, William Branson (facing compulsory retirement from the FBI) opted to pursue a master’s degree in counselling to help imprisoned adolescents he dealt with previously. Diane Johnson opted to seek certified credentials (after administering home-based schooling to her children) in order to provide elementary education to child ren. William and Diane are among a growing list of adults in pursuit of official degree programmes (Kiely, Sandmann Truluck 2004, p. 17). According to the University Continuing Education Association, the number of individuals aged above 65 years in the US is projected to increase to 90 million in 2030. Many of these individuals have enrolled in adult degree programmes. According to a report by National Center for Education Statistics, 33 percent of the country’s postsecondary institutions introduced distant-learning courses between 1997 and 1998. In addition, Lewis et al. (1999) reports that over 300 certificates and 1,200 degrees are offered by various learning institutions through distance learning. It is important to note that these courses and degree programmes have unique appeal to adult learners because they are time-and place independent. Therefore, this paper aims to explore strategies and theories for adult development and collaborative learning. Adult Learning Theo ry Kiely, Sandmann Truluck (2004) assert that the theory of adult learning is exceptionally diverse and intricate matter (p. 18). In the last two decades, several adult educators have endeavoured to map (theoretically) the margins of adult learning theory in order to assist experts manoeuvre the subject more efficiently. For instance, Mackeracher (1996) analysed adult education via the vibrant and versatile lens of a kaleidoscope. Merriam (1988) portrays adult education as a web and suggests a six-part template to assist adult educators manoeuvre through various relevant areas, such as theories of adult education as well as traits of adult learners.Advertising Looking for assessment on education? Let's see if we can help you! Get your first paper with 15% OFF Learn More In a more current study, Merriam (2001) defines adult education as an â€Å"ever-changing mosaic, where old pieces are rearranged and new pieces added† (p. 1). Furthermore, Merriam (20 01) incorporates conventional theories of adult education that lend credence on traits of individual adult learners as well as learning processes. Merriam and Caffarella (1999) provide the most inclusive theoretical framework for explaining and comprehending the diverse nature of adult learning theory. Their theoretical construct explores three areas: the characteristics of the adult learner, circumstances under which adult individuals learn, and the adult learning procedures. The following sections explore the theory of adult education that elucidates diverse aspects of adult education process. For adult educators who develop and control adult degree programs, the theory of adult learning provides a valuable instrument to manoeuvre the immense sphere of adult education, including hypothetical standpoints and their realistic applications (Kiely, Sandmann Truluck 2004, p. 19). Adult Learning Theory The adult learning theory (also known as Androgogy) was first suggested by Knowles et al. (1998). According to Knowles et al. (1998), the adult learning theory comprises of six doctrines. The first doctrine relates to the learner’s need to know: â€Å"how learning will be conducted, what learning will occur, and why learning is important† (Knowles et al., 1998, p. 133). The second doctrine, known as self-sufficient education, refers to the ability of a learner to control strategies and aims of learning. Third, previous knowledge of the learner influences education by producing prejudices and adults’ self-realization, offering rich resources and generating diversity among adult learners. The fourth doctrine is willingness to learn. Adults are usually willing to study when their life circumstance produce a desire to learn. Usually, adults fancy analytical approach to learning. For instance, adults learn better when learning is embedded in real-life experiences. The fifth doctrine is inspiration to study. The adults’ inspiration to learn is usually high especially if the knowledge acquired can enable them to work out key issues in their lives. Brookfield (1995) investigated four key procedures associated with adult learning. First, self-administered education lends credence on the procedure in which adults learners manage their learning process. First, adults establish their learning objectives, search for suitable resources, make decision regarding their education styles and assess their advancement.Advertising We will write a custom assessment sample on Adult Development and Collaborative Learning specifically for you for only $16.05 $11/page Learn More Second, in-depth reflection refers to the procedure of understanding the manner in which adult learners think critically and contextually. Third, tentative education emphasizes that adult learning should lend credence on the experiences of adults. Lastly, learning to learn is an integral component for adult development (Huang 2002, p. 30). Hu ang (2002) asserts that adult learning is a lifetime process that takes place at individual level. With respect to individual disparities, it is perfectly normal for adult learners to experience anxiety when they are subjected to a new learning environment. In addition, Huang (2002) states that adults must be motivated adequately to undertake learning because they have additional responsibilities (i.e. family and work). Therefore, adult educators must provide constructive environment at the appropriate time and provide relevant materials that are well organized in order to improve the prospects of success (p. 30). Constructivism Some researchers have suggested that adults could learn dynamically and construct novel ideas on the basis of their previous knowledge (Bruner 1996; Huang 2002). Under constructive approach, the role of educator is to facilitate the learning process. Huang (2002) asserts that circumstances symbolize the knowledge of the environment that affects interactions occurring between the learner and his/her settings. Therefore, the learning process is grounded upon active experience. In addition, he suggests that the learner should acclimatize his/her problem-solving skills to other subjects. An adult learner who lacks motivation will not recognize a problem. Therefore, the learning process should incorporate problems that capture interests of the learner. Thus, constructivist approach lends credence on enhancing the capability of a learner to solve his/her real-life problems. Consequently, problem-solving and free discovery are intertwined. This means that knowledge is vibrant and is constructed on the basis of course of discovery. Under constructivism, the educator is deemed as a guide as opposed to an instructor. The rationale for this argument is that learning facilitates interaction between the learner and the educator as opposed to result-based learning (Huang 2002, p. 29).Advertising Looking for assessment on education? Let's see if we can help you! Get your first paper with 15% OFF Learn More The role of social learning is also emphasized by Vygotsky (1978). For instance, Vygotskian theory lends credence on the significance of socio-cultural perspective in which learning occurs and the manner in which it influences the learning process (Vygotsky 1978). Vygotskian theory is also known as social constructivism because it lends credence on the role of interaction between educators and adult learners in cognitive development. A substantial part of the collaborative problem-solving approach is based on the zone of proximal development (ZPD), a concept developed by Vygotsky (Huang 2002, p. 29). Online Technology Huang asserts the crucial role of technology in adult learning. He categorically states that: Principal emphasis in education should be placed upon skills†¦skills in handling, in seeing and imaging, and in symbolic operations, particularly as these are related to the technologies that have made them so powerful in their human expression (Huang 2002, p. 29). Thus, technologies are deemed as cognitive instruments that can assist an adult student to elucidate his/her experiences as well as participate in constructive learning. Various technologies (i.e. World Wide Web, online chat rooms and courseware) are utilized to help adult learners engage in collaborative learning. For instance, the Web offers hypermedia ability to aid the learning process. Web publishing and hypermedia are online tools that usually incorporate information search engines. The search engines are used on regular basis to search and understand a variety of ideas generated by other learners. In addition, the Web offers massive information for adult students. For example, the adult learner can use the Web to generate his/her own ideas or search for relevant information to solve problems. Therefore, the Web is an important tool for constructivist education. Furthermore, newsgroups, chat rooms, listservs and Email enable adult learners to interact with their peers and access new knowledge. Synchronous and asynchronous conversations lends emphasis on the advancement of knowledge-creating groups where members share the knowledge created as well as procedures employed to create it (Huang 2002, p. 30). Constructivism in Adult Learning Interactive Learning Vygotsky (1978) asserts that adult students learn effectively when they collaborate with their peers. In other words, interactivity plays an important role in stimulating and motivating adult learners. In addition, online interactivity facilitates knowledge exchange between learners and educators. However, some adult learners do not engage in active interactions with their peers. Therefore, educators must help them to participate actively in group discussion. For example, educators can achieve this goal by developing discussion plans that require all adult students to take part in group conversation through coordinated communication instruments such as multi User Dungeons (MUD), online conferences or online c hat rooms. In addition, educators can request adult students to read and react to course materials via asynchronous communication instruments such as emails, news groups and listservs. Thus, significant feedback and response surface when adult learners appreciate the significance of their learning process. It is important to mention that interactions between adult students, educators and course material are essential elements required in distance learning (Huang 2002, p. 33). Collaborative Learning Social constructivists suggest that adult education should underline interaction between adult learners and their environments in order to augment collaborative learning. Developing a social conciliation environment can promote introspective responses and augment collaborative learning. This is an important aspect that must be emphasized by educators in order to promote critical thinking abilities among adult learners. In addition, novel technologies can augment learners’ interacti ons as well as promote collaborative efforts to amalgamate collective knowledge. In nutshell, constructivist approach emphasizes that instructors must strive to inculcate collaborative learning via social negotiation and reflection (Huang 2002, p. 33). Facilitating Learning A successful instructor must provide an enabling environment that permits adult learners to articulate their experiences in suitable ways. In addition, the environment should allow adult learners to pose questions as well as share their knowledge. In addition, distant learners will be willing to work hard and succeed if the learning environment is secure and motivating. Thus, constructivist approach provides adult learners more autonomy to choose and organize their learning procedures with their peers. Furthermore, under the constructivist approach, the educator facilitates the learning process. The constructivist approach also emphasizes that educators must supervise and certify the quality of collaborative lear ning. In addition, educators must provide adequate support, guidelines and directions for online students (Huang 2002, p. 33). Authentic Learning According to constructivist theory, the learning process ought to be authentic. In addition, the process should capture real-life experiences. According Huang (2002, p. 33), â€Å"constructivists emphasize the design of learning environments rather than instructional sequences†. In other words, adult students must acquire skills associated with their work experiences. This is an important aspect which must be addressed by educators and integrated in the adult learning process. Adult educators must also strive to integrate practical education in adult education. Furthermore, learning should be embedded in real-life issues, incidents or challenges which must be meaningful and interesting to adult students. In addition, educators must evaluate the traits of adult students so as to steer clear of pre-authentication. It is important to m ention that educators should involve adult learners in developing the curriculum. In other words, adult learners should have a say regarding what should be taught, the objectives of the curriculum and the relevant materials required for the course. Consequently, the knowledge of adult students will be authentic and meaningful (Huang 2002, p. 34). Learner-Centred Learning Adult learning theory and constructivist approach emphasize that adult learners should take charge of their learning process. In addition, these theories emphasize that learners should undertake learning via a problem-solving approach. In general, there are several hypotheses associated with adult distance learning. For example, adult distance learners are inspired and individually different, self-oriented, and extremely independent. Consequently, the prospects of Learner Centred Psychological Principles are in harmony with the hypotheses of adult distance learning. This is because the prospects for promoting lifeti me learning lean towards learner-oriented design of instruction which emphasize the active role of adult learners with respect to the development of learning programmes. Furthermore, self-oriented students set their goals, are extremely motivated, search for resources and assess their education process to achieve their objectives (Huang 2002, p. 34). High-Class Learning Constructivist approach lends credence on the learner’s ability to control the learning process. The approach also reduces the gap between the real-life experiences and the learning environment. Compared to conventional learning environment, online instructional media endows unlimited autonomy of control to the learner. In other words, an adult learner can access limitless number of information related to real-life experiences using search engines. As noted earlier, adult students must soak up external inputs and create ingenious ideas from their previous experiences. Huang (2002) asserts that adult learners n eed key thinking abilities to be able to confront and direct their lives. To put another way, adult learners should possess necessary skills to be able to evaluate the authenticity and quality of information available online. Adult students must also learn how to control, evaluate, review and convert information into precious knowledge (Huang 2002, p. 34). Conclusion Statistics show that the number of individuals aged above 65 years in the US is projected to increase to 90 million in 2030. Many of these individuals have enrolled in adult degree programmes. According to a report by National Center for Education Statistics, 33 percent of the country’s postsecondary institutions offer several distant-learning courses. In addition, Lewis et al. (1999) reported that over 300 certificates and 1,200 degrees are offered by various learning institutions through distance learning. It is important to note that these courses and degree programmes have unique appeal to adult learners beca use they are time-and place independent. Several empirical studies have been done to explore the role of collaborative learning in adult development. This paper has discussed several theories and strategies to enhance adult development and collaborative learning. As mentioned earlier, constructivist theories provide various strategies that educators can use to construct learner-oriented and collaborative settings that enhance learning processes and critical reflection. Kiely, Sandmann Truluck (2004) assert that the theory of adult learning is exceptionally diverse and intricate matter (p. 18). In the last two decades, several adult educators have endeavoured to map the margins of adult learning theory in order to assist experts manoeuvre the subject more efficiently. For instance, Mackeracher (1996) analysed adult education via the vibrant and versatile lens of a kaleidoscope. Online discussion groups have a number of characteristics such as collaborative, inquiry-based, project-ba sed, authentic, and discussion-based. In nutshell, educational theories, instructional strategies and other related factors are important for promoting adult development and collaborative learning. References Dillenbourg, P, Backer, M, Blaye, A O’Malley, C 1996, The evolution of research on collaborative learning, Elsevier, Oxford. Bruner, J 1996, The culture of education, Harvard University Press, Cambridge. Huang, H 2002, ‘Toward constructivism for adult learners in online learning environments’, British Journal of Educational Technology, vol. 33 no. 1, pp. 27-37. Kiely, R, Sandmann, L Truluck, J 2004, ‘Adult Learning Theory and the Pursuit of Adult Degree’, New Direction for Adult and Continuing Education, no. 103, pp. 17-30. Knowles, M, Holton F Swanson, R 1998, ‘The adult learner’, Computer and Education, vol. 31, pp. 229-242. Lewis, L, Snow, K, Farris, E Levin, D 1999, Distance Education at Postsecondary Education Institutions, National Center for Educational Statistics, Washington, D.C. Mackeracher, D 1996, Making Sense of Adult Learning, Culture Concepts, Toronto. Merriam, S 2001, Editor’s Notes: The New Update on Adult Learning Theory, Jossey-Bass, San Francisco. Merriam, S 1988, ‘Finding Your Way through the Maze: A Guide to Literature in Adult Learning’, Lifelong Learning: An Omnibus of Practice and Research, vol. 11no. 6, pp. 4–7. Vygotsky, L 1978, Mind in society, Harvard University Press, Cambridge.

Sunday, October 20, 2019

If le Fait Que Is Supposition, Use the Subjunctive

If le Fait Que Is Supposition, Use the Subjunctive The subjunctive after le fait que (the fact that) is optional: It depends on what you mean.When youre actually talking about  a fact, you do not need the subjunctive, as in: Le fait quil le faitThe fact that hes doing it(You know for a fact that hes doing it.)However, when youre talking about a supposition, you do need the subjunctive, as in:Le fait que tout le monde sacheThe fact that everyone knows(Youre supposing that everyone knows, but you dont know it for a fact.) The Heart of the Subjunctive This goes to the heart of the subjunctive  mood, which  is used to express actions or ideas that are subjective or otherwise uncertain, such as will/wanting, emotion, doubt, possibility, necessity and judgment.   The subjunctive can seem overwhelming, but the thing to remember is: the subjunctive subjectivity or  unreality. Use this mood enough and it will become second nature...and quite expressive. The French subjunctive  is nearly always found in dependent clauses introduced by  que  or  qui, and the subjects of the dependent and main clauses are usually different. For example:      Je veux que tu le fasses. I want you to do it.  Ã‚  Ã‚  Ã‚  Il faut que nous partions. It is necessary that we leave. Dependent Clauses Take the Subjunctive When They: Contain verbs and expressions that express someones will, an  order, a need, a piece of advice or a desire.Contain verbs and expressions of emotion or feeling, such as fear, happiness, anger, regret, surprise, or any other sentiments.Contain verbs and expressions of doubt, possibility, supposition  and opinion.Contain verbs and expressions, such as  croire que  (to believe that),  dire que (to say that),  espà ©rer que (to hope that),  Ãƒ ªtre certain que (to be certain that),  il paraà ®t que  (it appears that),  penser que  (to think that),  savoir que  (to know that),  trouver que  (to find/think that) and  vouloir dire que (to mean that), which only require the subjunctive when the clause is  negative or interrogatory. They  do  not  take the subjunctive when they are used in the affirmative, because they express facts that are considered certain- at least in the speakers mind.Contain French  conjunctive phrases  (locutions conjonctiv es), groups of two or more words that have the same function as a conjunction and imply supposition.   Contain the  negative pronouns  ne ... personne  or  ne ... rien, or the  indefinite pronouns  quelquun  or  quelque chose.Follow main clauses containing superlatives. Note that in such cases,  the subjunctive is optional, depending on  how concrete the speaker feels about what is being said.   Why le Fait Que Sometimes Takes the Subjunctive Le fait que (the fact that) is an example of number 4:  an expression of doubt, possibility, supposition  and opinion. There are many expressions in this category and for all of them, its the same. If they are expressions of uncertainty and subjectivity, they, of course, do take the subjunctive. When they talk about an actual fact, they do not take the subjunctive. So think before you write or speak these common expressions, which most times take the subjunctive: accepter que  Ã‚  to acceptsattendre ce que   to expectchercher ... qui   to look fordà ©tester que   to hatedouter que  Ã‚  to doubt thatil est convenable que  Ã‚  it is appropriate/proper/fitting/suitable thatil est douteux que  Ã‚  it is doubtful thatil est faux que  Ã‚  it is false thatil est impossible que  Ã‚  it is impossible thatil est improbable que  Ã‚  it is improbable thatil est juste que  Ã‚  it is right/fair thatil est possible que  Ã‚  it is possible thatil est peu probable que  Ã‚  it is improbable thatil nest pas certain que  Ã‚  it is not certain thatil nest pas clair que  Ã‚  it is not clear thatil nest pas à ©vident que  Ã‚  it is not obvious thatil nest pas exact que  Ã‚  it is not correct thatil nest pas probable que  Ã‚  it is improbable thatil nest pas sà »r que  Ã‚  it is not certain thatil nest pas vrai que  Ã‚  it is not true thatil semble que  Ã‚  it seems thatil se peut que  Ã‚  it may be thatle fait que     the fact thatnier que  Ã‚  to deny thatrefuser que  Ã‚  to refusesupposer que  Ã‚  to suppose, hypothesize Additional Resources The French SubjunctiveFrench ConjunctionsThe Subjunctivator!Quiz: Subjunctive or indicative?

Saturday, October 19, 2019

Primary lung cancer Essay Example | Topics and Well Written Essays - 500 words

Primary lung cancer - Essay Example It is vastly important to distinguish between SCLC and NSCLC through their histology as the treatment differs ("Types of," 2009). Although, SCLC grows and spreads quickly to other areas of the lung, it is also more responsive to treatment. SCLC accounts for 20 % of all lung cancers ("Types of," 2009). Exposure to radon, asbestos and uranium increases the risk of SCLC along with cigarette smoke. Small cell lung cancer is divided into two stages; namely, limited and extensive. Limited stage accounts for the presence of cancer in lymph nodes and in between the tissues present in one lung. While in the latter stage, cancer has spread to other organs of the body. The symptoms increase as the cancer advances: from coughing to swelling of hands and face, fatigue and even paralysis. Diagnosis is done through CT scan, chest x-ray, sputum cytology, bronchoscopy, etc. Radiation therapy and chemotherapy play a major role in combating SCLC whereas; surgery plays little or no role. This is because in about 70% of the patients, the tumor has already spread to other organs ("Small-Cell," 2009). Moreover, the survival time is about two years in the extensive stage. Though, there are cases where early diagnosis of SCLC has benefitted from surgical removal of the tumor. Non-small cell lung cancer (NSCLC) has many different types based on their histology; which makes up about 75% of all lung cancers.

Friday, October 18, 2019

Management Problem Solving - Systems Intervention Strategy (SIS) and Essay

Management Problem Solving - Systems Intervention Strategy (SIS) and Soft Systems Methodology - Essay Example Once they manage to get an order, administrative will be informed. Administrative staff then gets the order and starts planning the production. The second group is the Particular Sales Staff that administrative staffs often work with them. Their request has more priority that sales staffs taken orders. This means that if a particular sale staff and a sale staff request an order at the same time, the particular order will be selected first. This causes a delay to order delivery to non-particular requests or even may cause another plant get the order. This is what the staffs are concerning about and they want too find a solution for it. In figure one, the structure of the cement business is shown. Cement business itself is a part of a major conglomerate in UK that has separate plants scattered around the country. Each plant may produces the same cement product as another plant at the same or different region does. In figure two, the entities inside the current Cement Business and their relations are shown. In this figure, both plant1 and plant2 are competing on the upper order. The middle order is only requested by Plant2. The lower order is given to the plant1 by a particular staff. Administrative "The purpose of the root definition is to express the core purpose of some purposeful activity system."3 In table 1,every entity that has a kind of input and output with the system is stated. Each person sees the system on his/her own view. In this stage, we try to compare the conceptual model with its real model. We need to give the access to an order to only one staff at the same time. We need to reduce the points between the particular staff and the administrative staff. We also need to use a group of staffs and a group of administrative staffs. 6 and 7. The next stage is to see if the we can implement the conceptual model in real world or not. In fact

Summarize the Article Essay Example | Topics and Well Written Essays - 250 words

Summarize the Article - Essay Example population. These results support the notion that those with exceptional longevity may interact with environmental and lifestyle factors differently than others. Lifestyle factors play a larger role in human lifespan than due to genetic factors. The presence of longevity genes in people with exceptional longevity counters the presence of disease-associated genes. To live long and to live a healthy life is the normal expectation of a human being. Two significant factors have been identified for the important role they play in longevity and they are lifestyle and genetic factors. The relative contributions of these two factors are a matter of conjecture. But the scale tilts more in favor of genetic contribution to a healthy life span in those with exceptional longevity may be greater than that in the general population and several genes have been found to be associated with longevity in these individuals. But in studies the lifestyle of this population has received less

The soccer team Essay Example | Topics and Well Written Essays - 1000 words - 1

The soccer team - Essay Example the chosen group is indeed a discourse community when the characteristics are presented and qualified through the lens being used which is the aforementioned six characteristics. One can never know all the necessary information just by observing the group because there might still be other information that are not observable. Therefore, in addition to observing, this writer also used interview to gather the necessary information used in the analysis. The interview was done with a member of the group, Sharon Simons. Swales says that, â€Å"A discourse community has a broadly agreed set of common public goals† (471). The interviewee says that as a team, their goal is to win the Atlantic 10 Season, the Atlantic 10 championship and the National Collegiate Athletic Association Women’s Soccer Championship. Obviously, the group does not just exist to perform or play but they have a goal that they are trying to reach. Secondly, â€Å"A discourse community has mechanism of intercommunication among its members† (471). Asked about this, the interviewee says that thee team does not communicate in the field only but the members also talk off field to bridge the gap in their communications. She also claims that they do their planning during practices which often happen two to three times a week. Moreover, they do immediate planning during games and half-time breaks or whenever there are substitutes in the game. They do the talking and planning throughout the game because as it is observ ed in soccer games, there may be changes that might affect what could have been planned before the game or accidents that may cause change in plans. The third characteristic mentioned by Swales is, â€Å"A discourse community uses its participatory mechanisms primarily to provide information and feedback† (472). True enough, the soccer team reflects this. As mentioned earlier, the team meets for practice, two to three times a week which is a fairly good number of times for good communication to

Thursday, October 17, 2019

International HRM Essay Example | Topics and Well Written Essays - 2500 words

International HRM - Essay Example It is a given fact that different forms of expatriate assignments are very important to any corporation that has presence in different nations for functional success (Adler, 1983). Incorporating any expatriate to the functional as well as the developmental environment of an organization is also necessary to ensure that expatriate has a healthy working atmosphere around him or her. Many researchers and HR professionals are interested in understanding how to facilitate expatriate adjustment in order to make sure that the global projects that invariably involved a considerable amount of investment prove to be successful. Many different factors are involved in expatriate adjustment and it is the responsibility of the human resources management to facilitate this process. This study aims to explore the various actions that the HR can take to facilitate expatriate adjustment in a smooth manner. Many researches from consultancies (GMAC, 2006) have shown a consistent and substantial growth i n the number of people who have been sent abroad by their employee. In light of this, it is necessary to understand the different ways in which an organization can ease the process and make it comfortable for the employees to adjust to a different country and organizational set up. According to the model of international adjustment developed by Black, Mendenhall and Oddou (1991), expatriate adjustment has three inherent domains; one is adjustment to an overseas workplace, adjustment to interacting with the host nationals and adjustment to the overseas work atmosphere. As per the research done by Navas et al (2007), there are six domains that are crucial in expatriate adjustment, and they are politics and government, work, economics, social relations, family relations and ideology. According to Navas, the domains are listed based on the increasing resistance to change. For example, employees would easily adjust to the government rules, work, economics and so on, but they would not ea sily adjust the belief, value systems and ideology of the host country. The Human Resources department can decide on working on each of these aspects based on the tenure as well as the previous experience of the employees. Expatriate adjustment has a good influence on the performance of the employees and if there are, some issues related to adjustment there are high chances that the performance may get affected in various degrees. In this study, the various factors that need to be addressed by the HR in order to ensure a smooth a transition. Choice of the Right Person Before the decision related to selecting an employee for an expatriate assignment is made, it is necessary to explore different aspects. One such aspect is flexibility. It is necessary to understand the level of flexibility that an employee brings in to the organization (Feldman and Thompson, 1993). If an employee finds it difficult to work in different groups or teams within the same organization in the same location, there are chances that he or she may find it even more difficult to adjust in a foreign location. Hence, the HR personnel should ensure that the person has displayed a good amount of flexibility in their current roles before sending them for an overseas assignment. It is also important to understand the manner in which employee responds to change in the organization. In addition, it is also necessary to test the aptitude of the person to live abroad. The employee should be open to the idea of living in another country for the fixed tenure. In

The Food and Drug Administration should regulate the content of Essay

The Food and Drug Administration should regulate the content of vitamins and supplements to ensure the American public is safe - Essay Example Dietary supplements are defined under the Dietary Supplement Health and Education Act (DSHEA) as products that contain the one or a combination of the following dietary ingredients: vitamins, minerals, herbs and other botanicals, amino acids, hormones, concentrate or metabolites. Supplements usually come in the form of pill, tablet, liquid form or capsule with some being administered intravenously. They differ from pharmaceutical drugs for most of them have unproven therapeutic benefits and is considered more like a food product with the exception that they bear a ‘dietary supplement’ label. With the influx of dietary supplements in the marketplace, claims of medical benefits abound with little scientific proof. The problem is that human society have become so conscious with their health but so lazy to maintain it by exercise and proper food intake that dietary supplements have become so popular and so much in demand. In the face of this dilemma, there is only one possible resolution: for the FDA to strictly monitor and control the production and entry to market of dietary supplements. This paper aims to underscore this choice of action through an analysis of facts and events. A preliminary analysis to serve as a platform for a full scale research is presented in the following passages. Vitamins and minerals have long been recognized by medical science to have beneficial medical effects. For example, Vitamin C more commonly known as ascorbic acid, have been shown to stimulate the production and function of white blood cells thereby boosting the body’s immunity. It has also been found to prevent the formation of carcinogenic compounds such as nitrosamines. Vitamin A, a pale yellow primary alcohol, improves eyesight by aiding in the formation of mucous membranes and tear glands. Almost all vitamins have some

Wednesday, October 16, 2019

International HRM Essay Example | Topics and Well Written Essays - 2500 words

International HRM - Essay Example It is a given fact that different forms of expatriate assignments are very important to any corporation that has presence in different nations for functional success (Adler, 1983). Incorporating any expatriate to the functional as well as the developmental environment of an organization is also necessary to ensure that expatriate has a healthy working atmosphere around him or her. Many researchers and HR professionals are interested in understanding how to facilitate expatriate adjustment in order to make sure that the global projects that invariably involved a considerable amount of investment prove to be successful. Many different factors are involved in expatriate adjustment and it is the responsibility of the human resources management to facilitate this process. This study aims to explore the various actions that the HR can take to facilitate expatriate adjustment in a smooth manner. Many researches from consultancies (GMAC, 2006) have shown a consistent and substantial growth i n the number of people who have been sent abroad by their employee. In light of this, it is necessary to understand the different ways in which an organization can ease the process and make it comfortable for the employees to adjust to a different country and organizational set up. According to the model of international adjustment developed by Black, Mendenhall and Oddou (1991), expatriate adjustment has three inherent domains; one is adjustment to an overseas workplace, adjustment to interacting with the host nationals and adjustment to the overseas work atmosphere. As per the research done by Navas et al (2007), there are six domains that are crucial in expatriate adjustment, and they are politics and government, work, economics, social relations, family relations and ideology. According to Navas, the domains are listed based on the increasing resistance to change. For example, employees would easily adjust to the government rules, work, economics and so on, but they would not ea sily adjust the belief, value systems and ideology of the host country. The Human Resources department can decide on working on each of these aspects based on the tenure as well as the previous experience of the employees. Expatriate adjustment has a good influence on the performance of the employees and if there are, some issues related to adjustment there are high chances that the performance may get affected in various degrees. In this study, the various factors that need to be addressed by the HR in order to ensure a smooth a transition. Choice of the Right Person Before the decision related to selecting an employee for an expatriate assignment is made, it is necessary to explore different aspects. One such aspect is flexibility. It is necessary to understand the level of flexibility that an employee brings in to the organization (Feldman and Thompson, 1993). If an employee finds it difficult to work in different groups or teams within the same organization in the same location, there are chances that he or she may find it even more difficult to adjust in a foreign location. Hence, the HR personnel should ensure that the person has displayed a good amount of flexibility in their current roles before sending them for an overseas assignment. It is also important to understand the manner in which employee responds to change in the organization. In addition, it is also necessary to test the aptitude of the person to live abroad. The employee should be open to the idea of living in another country for the fixed tenure. In

Tuesday, October 15, 2019

Performance of Stock Exchange of Thailand Essay

Performance of Stock Exchange of Thailand - Essay Example One of the most salient features of stock exchange is that it provides liquidity to investors who are often in need of trading their securities without loss of time and value. One of the most important functions of the stock market is that it can serve as a strong indicator of price discovery. Since securities held by shareholders represent claims against the real assets of a firm, their price indicates the return that their assets can fetch from the market, if they are realized. This important function of price discovery provides necessary impetus to the organizations to issue new stock and arrange relatively cheaper funds from external sources to fund the future expansion. The return from the shareholdings of an investor is the strong factor that keeps him/her to maintain investment with the same firm and inspire him to buy more of the same firm. However, the size of market return is not reliable as it is subject to variations over time owing to many factors, mostly beyond the control of an individual firm. The factors that determine and influence the return and/price of stocks are coined as the determinants of stock market return. ... However, these forces are decided by many factors, which include both internal and external variables that can influence the investment decision of investors. From another perspective, these factors may be categorized as systematic factors (economic, political or sociological changes) that are common to all securities and unsystematic factors (company specific factors), which are unique to certain industries or firms. This chapter is meant to document the studies and researches undertaken across different parts of the world on the subject matter of stock market return and its determinants. This literature review covers a wide spectrum of empirical as well as non-empirical studies conducted to study the economic as well as non-economic variables, which influence the market behavior and return individually and collectively. 2.0 Stock Market In today's investment arena stocks have been widely accepted as the most important investment avenue for individual as well as institutional investors. A stock is referred to as a financial claim against the real assets of a firm. It represents a valid legal claim in favor of its holder for the right to get periodical return and capital appreciation, if any. It not only represents the partial or pro-rata ownership of the investors in a firm but it also allows them to influence the decisions affecting the day to day affairs of the company. One of the most appealing features of the investment in stock is that it provides maximum protection and liquidity to the investors by allowing easy trading at stock exchange at agreeable prices. Even though stock represents ownership in a company, it does not mean that the shareholders are liable for the

Monday, October 14, 2019

Solid Dispersion System in Drug Delivery

Solid Dispersion System in Drug Delivery The oral route remains the preferred route of drug administration due to its convenience, good patient compliance and low medicine production costs. In order for a drug to be absorbed into the systemic circulation following oral administration, the drug must be dissolved in the gastric fluids. The active pharmaceutical ingredient in a solid dosage form must undergo dissolution before it is available for absorption from the gastrointestinal tract.1 Currently, approximately 40% of the marketed immediate release (IR) oral drugs are categorized as practically insoluble ( 1.1 Biopharmaceutics classification system The Biopharmaceutical Classification System (BCS) was introduced in the mid-1990s to classify the drug substances with respect to their aqueous solubility and membrane permeability. BCS is a useful tool for decision-making in formulation development from a biopharmaceutical point of view. Solubility improvement strategies are required for Class II and Class IV drugs. 1.2 Approaches to improve the solubility or to increase the available surface area for dissolution Physical modifications Particle size Micronization Nanosuspensions Modifications of the crystal habit Polymorphs Pseudopolymorphs (including solvates) Complexation/solubilization Use of surfactants Use of cyclodextrins Drug dispersion in carriers Eutectic mixtures Solid dispersions (non-molecular) Solid solutions Chemical modifications Soluble prodrugs Salts 1.3 Solid Dispersions The term solid dispersion refers to a group of solid products consisting of at least two different components, generally a hydrophilic matrix and a hydrophobic drug. The matrix can be either crystalline or amorphous. The drug can be dispersed molecularly, in amorphous particles (clusters) or in crystalline particles.7 Much of the research that has been reported on solid dispersion technologies involves drugs that are poorly water-soluble and highly permeable to biological membranes as with these drugs dissolution is the rate limiting step to absorption. Hence, the hypothesis has been that the rate of absorption in-vivo will be concurrently accelerated with an increase in the rate of drug dissolution. Therefore, solid dispersion technologies are particularly promising for improving the oral absorption and bioavailability of BCS Class II drugs. 1.3.1 Types of solid dispersions On the basis of release mechanisms and molecular arrangement in the matrix, solid dispersions are distinguished into following types9: A. Simple eutectic mixture: Eutectic mixture is prepared by rapid solidification of fused melts of two components that show a complete liquid miscibility with negligible solid-solid solubility. It involves loose atomic or molecular interaction and not on the formation of chemical bonds. When the eutectic mixture is exposed to gastrointestinal fluids, both the poorly soluble drug and the carrier may simultaneously crystallize out as a very small particles result in an increased the surface area and improved dissolution and absorption of the drug. B. Solid solution: A solid solution represents a homogenous one phase system, where the solid solution is dissolved in a solid solvent and the two components crystallize together. The solid solution achieves faster dissolution than a eutectic mixture because the drug particles in a solid solution are reduced to molecular size and dissolution of the drug takes place in the solid state prior to the exposure to the liquid medium. C. Glass solution: It is a homogenous glassy system in which a solute dissolves on glassy solvent results in increased dissolution and absorption of the drug. It is characterized by a transparency and brittleness below the glass forming temperature. Glass solution is a metastable and the strength of the chemical bonding is much less as compared to solid solution. Therefore, the release of the drug was found to be faster than a solid solution. D. Amorphous precipitations in crystalline carrier: An amorphous form of a drug produces faster dissolution rate. The drug may precipitate out in an amorphous form in a crystalline carrier from solid dispersions prepared by melting or solvent method. A strong interaction between the drug and carrier resulting in the formation of channels within the matrix seems to be a possible mechanism for improved dissolution of the drug. E. Compound or complex formation: The formation of a complex between the drug and the carrier may either decrease of increase the dissolution and the absorption rate of the drug. The formation of soluble complex with low association constant resulted in increased rate of dissolution and absorption. The enhancement in dissolution rate of the drug can be ascribed to An increasing solubility of the drug because of its amorphous state or small particle size (Kelvins law)9,10 An increased surface area available for drug dissolution because of the small size of the drug particles11,12 An improvement in wetting of the drug caused by the hydrophilic carrier13,14 1.3.2 Advantageous properties of solid dispersions Management of the drug release profile using solid dispersions is achieved by manipulation of the carrier and solid dispersion particle properties. Parameters such as carrier molecular weight and composition, drug crystallinity and particle porosity and wettability, when successfully controlled, can produce improvements in bioavailability.16 a. Particles with reduced particle size: Molecular dispersions, as solid dispersions, represent the last state on particle size reduction, and after carrier dissolution the drug is molecularly dispersed in the dissolution medium. Solid dispersions apply this principle to drug release by creating a mixture of a poorly water soluble drug and highly soluble  carriers. A high surface area is formed, resulting in an increased dissolution rate and consequently, improved bioavailability. b. Particles with improved wettability: Strong contribution to the enhancement of drug solubility is related to the drug wettability improvement in solid dispersions. It was observed that even carriers without any surface activity, such as urea improved drug wettability. Carriers with surface activity, such as cholic acid and bile salts, when used, can significantly increase the wettability properties of drugs. Moreover, carriers can influence the drug dissolution profile by direct dissolution or co-solvent effects. c. Particles with higher porosity: Particles in solid dispersions have been found to have a higher degree of porosity. The increase in porosity also depends on the carrier properties, for instance, solid dispersions containing linear polymers produce larger and more porous particles than those containing reticular polymers and, therefore, result in a higher dissolution rate. The increased porosity of solid dispersion particles also hastens the drug release profile. d. Drugs in amorphous state: Poorly water soluble crystalline drugs, when in the amorphous state tends to have higher solubility. The enhancement of drug release can usually be achieved using the drug in its amorphous state, because no energy is required to break up the crystal lattice during the dissolution process. 1.3.3. Carriers used in solid dispersions Many carriers of natural, semi-synthetic and synthetic types are being used which include natural carbohydrates, semi-synthetic and synthetic hydrophilic polymers. S.No:  1 Nature of carrier:  Sugars Name of the carrier:  Dextrose, sorbitol, sucrose, fructose,maltose,galactose, xylitol, mannitol S.No:  2 Nature of carrier:  Acids Name of the carrier:  Citric acid, tartaric acid and succinic acid S.No:  3 Nature of carrier:  Polymorphic materials Name of the carrier:  Polyvinyl pyrrolidone (PVP), polyethylene glycols, hydroxyl propylmethylcellulose (HPMC), guargum, xanthan gum, sodium alginate, methyl cellulose, pectin, hydroxyl ethyl cellulose (HEC), hydroxyl propyl cellulose (HPC) and dextrins. S.No:  4 Insoluble or enteric Nature of carrier:  polymer Name of the carrier:  Hydroxy propyl methyl cellulosepthalate, eudragit RL, eudragit L 100, eudragit S100, eudragit RS. S.No:  5 Nature of carrier:  Surfactants Name of the carrier:  Polyethylene stearate, poloxamer 188, tweens and spans. S.No:  6 Nature of carrier:  Miscellaneous Name of the carrier:  Nicotinic acid, succinamide, dextrans, gelatin, poly vinyl alcohol, urea, cyclodextrins, skimmed milk etc., Table 1.2 Various carriers used in solid dispersions 1.3.4. Preparation techniques of solid dispersions The following are the major processes for the preparation of solid dispersions. A. Solvent evaporation method: In this method, the physical mixture of two components is dissolved in a common solvent and followed by the evaporation of solvent. The advantages of this method are low temperature requirements for the preparation of dispersion and thermal decomposition of drugs and carriers can be prevented. The higher cost of production, incomplete removal of solvent, adverse effects of solvent on the chemical stability of the drug and selection of common solvent are the drawbacks of this method. B. Melting method (Fusion method): The physical mixture of drug and water- soluble carrier was heated to melt and the molten mixture was then cooled and solidified mass was crushed, pulverized and sieved. The melting point of a binary system depends on its composition and proper manipulation of drug carrier ratios. Decomposition should be avoided due to fusion time and the rate of cooling. C. Kneading method: The physical mixture of drug and carrier were triturated using small quantity of organic solvent and water mixture, usually alcohol and water (1:1v/v). The slurry is kneaded for 45 minutes and dried at 45 °C. The dried mass is pulverized and sieved through sieve no. 60 and the fraction was collected. The advantages of this method are low temperature requirements for solid dispersion preparation and usage of organic solvent is less. This method of preparation avoids thermal degradation of drug and employs less quantity of organic solvents. D. Melting solvent method: This method involves dissolving the drug in a suitable solvent and the incorporation of the solution directly into the molten carrier. This method possesses the advantages of both solvent and melting methods. E. Supercritical fluid methods: Supercritical fluid methods are mostly applied with carbon dioxide (CO2), which is used as either a solvent for drug and matrix or as an antisolvent. This technique consists of dissolving the drug and the carrier in a common solvent that is introduced into a particle formation vessel through a nozzle, simultaneously with CO2. When the solution is sprayed, the solvent is rapidly extracted by the SCF, resulting in the precipitation of solid dispersion particles on the walls and bottom of the vessel. This technique does not require the use of organic solvent and since CO2 is considered environmentally friendly, this technique is referred to as solvent free. This technique is known as Rapid Expansion of Supercritical Solution (RESS). F. Lyophilization/ Freeze Drying: This technique is an alternative to the solvent evaporation method. Here the drug and carrier are dissolved in common solvent, frozen and sublimed to obtain a lyophilized molecular dispersion. G. Melt agglomeration process: This technique is used to prepare solid dispersion where a binder acts as a carrier. The solid dispersion is prepared by heating binder, drug and excipient to a temperature above the melting point or spraying the dispersion of drug in the molten binder on the heated excipients using a high shear mixer. The effect of binder type, method preparation and particle size are the critical factors influencing the solid dispersion preparation by this method. These parameters results in various dissolution rates, mechanism of agglomerate formation and growth, agglomerate size and distribution. 1.3.5. Limitations of solid dispersion systems: Problems limiting the commercial application of solid dispersions are: Laborious and expensive method of preparation. Reproducibility of physico-chemical characteristics. Difficulty in incorporating into the formulation of dosage forms. Crystallization of the amorphous drug in the dispersion. Poor scale up of manufacturing process and physical and chemical stability of drug and the vehicle. 1.4 FDTs: Fast-disintegrating and fast-dissolving tablets are becoming popular as novel delivery systems for drug administration. They are more convenient for children, elderly patients, patients with swallowing difficulties, and in the absence of potable liquids. The most desirable formulation for use by the elderly is one that is easy to swallow easy to handle. Taking these requirements into consideration, attempts have been made to develop a fast-disintegrating tablet. Since such a tablet can disintegrate in only a small amount of water in the oral cavity, it is easy to take for any age patient, regardless of time or place. For example, it can be taken anywhere at anytime by anyone who do not have easy access to water. It is also easy to dose the aged, bedridden patients, or infants who have problems swallowing tablets and capsules. Recently, many companies have researched and developed various types of fast-disintegrating dosage forms.18 These tablets display a fast and spontaneous de-aggregation in the mouth, soon after the contact with saliva, though they can be handled or extracted from the package without alteration. The active agent can thus rapidly dissolve in the saliva and be absorbed through whatever membrane it encounters, during deglutition, unless it is protected from pre-gastric absorption. To fulfill these requirements, tablets must be highly porous, incorporating hydrophilic excipients, able to rapidly absorb water for a rapid deaggregation of the matrix. Different technological techniques, such as freeze drying or molding or direct compression are currently employed to prepare the formulations of this type present on the pharmaceutical market. 1.4.1 Advantages of Fast Disintegrating Drug Delivery System (FDDS) 19,20 Ease of administration to patients who refuse to swallow a tablet, such as pediatric and geriatric patients, mentally ill, disabled and uncooperative. Convenience of administration and accurate dosing as compared to liquids. No need of water to swallow the dosage form, which is highly convenient feature for patients who are traveling and do not have immediate access to water. Good mouth feel property of FDDS helps to change the basic view of medication as bitter pill, particularly for pediatric patients. Ability to provide the advantages of liquid medication in the form of solid preparation. Rapid dissolution of drug and absorption, which may produce rapid onset of action. Some drugs are absorbed from the mouth, pharynx and oesophagus as the saliva passes down into the stomach; in such cases bioavailability of drugs is increased. Pregastric absorption can result in improved bioavailability and as a result of reduced dosage, improved clinical performance through a reduction of unwanted effects. 1.4.2 Approaches for fast disintegrating tablets A. Patented technologies Currently, four fast-dissolving/disintegrating technologies have reached the U.S. market: Zydis (R.P. Scherer, Inc.) WOWTAB (Yamanouchi Pharma Technologies, Inc.) OraSolv (Cima Labs, Inc.) DuraSolv (Cima Labs, Inc.) B. Three others are available outside the U.S. Flash Dose (Fuisz Technologies, Ltd.), Flash tab (Prographarm Group), OraQuick (KV Pharmaceutical Co., Inc.) Nanocrystal Technology C. Conventional technologies Freeze -drying or lyophilization Tablet Molding Direct compression Spray drying Sublimation Mass extrusion Direct compression It is the easiest way to manufacture tablets. Conventional equipment, commonly available excipients and a limited number of processing steps are involved in direct compression. Also high doses can be accommodated and final weight of the tablet can easily exceed that of other production methods. Directly compressed tablets disintegration and solubilization depends on the single or combined action of disintegrates, water soluble excipients and effervescent agent. Disintegrate efficacy is strongly affected by tablet size and hardness. Large and hard tablets have a disintegration time more than that usually required. As consequences, products with optimal disintegration properties often have medium to small size and /or high friability and low hardness. Breakage of tablet edges during handling and tablet rupture during the opening of blister, all results from insufficient physical resistance. Disintegrants have a major role in the disintegration and dissolution process of mouth dissolving Tablets made by direct compression. To ensure a high disintegration rate, choice of suitable type and an optimal amount of disintegrant is important. Other formulation components such as water soluble excipients or effervescent agents can further enhance dissolution or disintegration properties. But the main drawback of using effervescent excipients is their highly hygroscopic nature. The understanding of disintegrant properties and their effect on formulation has advanced during the last few years, particularly regarding so called superdisintegrants. Disintegration efficiency is based on a force equivalent concept, which is the combined measurement of swelling force development and amount of water absorption. Force equivalent expresses the capability of disintegrant to transform absorbed water into swelling force. The optimization of tablet disintegration was defined by means of disintegrant critical concentration. Below this concentration, the tablet disintegration time is inversely proportional to disintegrate concentration and above that disintegration time remains approximately constant or even increases. The simultaneous presence of disintegrate with a high swelling force called disintegrating agent and substances with low swelling force ( starch, cellulose and direct compression sugar) defined as, swelling agent was claimed to be a key factor for the rapid disintegration of the tablet, which also offers physical resistance. 1.4.3 Mechanism of tablet disintegration and water absorption When mouth dissolving tablets placed in the mouth, upon contact with saliva the tablet disintegrates or dissolve instantaneously. The mechanisms involved in the tablet disintegration mechanisms are Swelling Wicking (capillary) Deformation Particle repulsive forces Chemical reaction (acid base reaction) a. Swelling Not all disintegrates swell in contact with water swelling is believed to be a mechanism in which; certain disintegrating agents (like starch) impart their disintegrating effect. By swelling in contact with water, the adhesiveness of other ingredients in a tablet is overcome causing the tablet to disintegrate. b. Wicking (porosity and capillary action) Effective disintegrants that do not swell are believed to impart their disintegrating action through porosity and capillary action. Tablets porosity provides a way for the penetration of fluid into tablets. The disintegrants particles (with cohesiveness and compressibility) themselves act to enhance porosity and provide these capillaries into the tablets. Liquid is drawn up or wicked into these ways by capillary action and rupture the inter-particulate bonds causing the tablet to break into small parts. c. Deformation Starch grains are generally thought to be elastic in nature that is the grains that are deformed under pressure will return to their original shape when that pressure is removed. But, with the compression forces involved in tabletting, these grains are permanently deformed and are said to be energy rich with these energies being released upon exposure to water, that is the ability for starch to swell is higher in energy rich starch grains than in starch grains that have not been deformed under pressure. It is believed that no single mechanism is responsible for the action of most disintegrants. But rather, it is more likely the results of interrelationships between these major mechanisms. d. Due to disintegrating particle/particle repulsive forces: Another mechanism of disintegration attempts to explain the swelling of tablets made with non-swellable disintegrants. Guyot-Hermann has proposed a particle repulsion theory based on the observation that nonswelling particle also causes disintegration of tablets. The electric repulsive forces between particles are the mechanism of disintegration and water is required for it. Researchers found that repulsion is secondary to wicking. e. Chemical reaction (acid base reaction) Disintegration of tablet included with citric acid and tartaric acid along with the sodium bicarbonate, sodium carbonate, potassium carbonate; these react in contact with water to liberate carbon dioxide that disrupts the tablet. Name of the Product:  Imodium Lingual Active Ingredients:  Loperamide hydrochloride Dose:  2 mg Name of the Product:  Pepcidin Rapitab Active Ingredients:  Famotidine Dose:  20mg and 40 mg Name of the Product:  Mosid MT Active Ingredients:  Mosapride citrate. Dose:  2.5mg and 5mg Name of the Product:  Calritin Reditabs Active Ingredients:  Loratadine Dose:  10 mg Name of the Product:  Nimulid MD Active Ingredients:  Nimesulide Dose:  50mg and 100mg Name of the Product:  Zyrof Meltab Active Ingredients:  Rofecoxib Dose:  50 mg Name of the Product:  Feldene Melt Active Ingredients:  Piroxicam Dose:  10mg and 20 mg Name of the Product:  Maxalt-MLT Active Ingredients:  Rizatriptan Dose:  5mg and 10 mg Name of the Product:  Pepcid RPD Active Ingredients:  Famotidine Dose:  20mg and 40 mg Name of the Product:  Zyprexa Zydis Active Ingredients:  Olanzapine Dose:  5mg, 10mg, 15mg and 20 mg Name of the Product:  Zofran ODT Active Ingredients:  Ondansetron Dose:  4 mg and 8 mg Name of the Product:  Remeron Soltab Active Ingredients:  Mirtazepine Dose:  15mg, 30mg and 45 mg Name of the Product:  NuLev Active Ingredients:  Hyoscyamine sulfate Dose:  0.125 mg Table 1.3 Marketed fast disintegrating tablets Piroxicam, a non-steroidal anti inflammatory agent, belonging to BCS class II is widely used as a first line drug in the symptomatic relief of rheumatoid arthritis and osteoarthritis. Its low aqueous solubility has to be overcome through formulation strategies. Skimmed milk can be used as a drug carrier as it is inexpensive, easily available, biodegradable, and does not exhibit toxicity problems as experienced with PEG and PVP.24-26 Polymers  as  carriers  also  have  limitations  in  enhancing  Ã‚  the  Ã‚  solubility  of poorly  soluble drugs  due to  their  high viscosity. So the use of skimmed milk in the formulation of the SD of the drugs with limited aqueous solubility may be a potential and cost effective way to overcome the problem.27 Skimmed milk is a colloidal suspension of casein micelles, globular proteins and lipoprotein particles. The principal casein fractions are a-s1, a-s2, b-casein and k-casein. b-casein is amphiphilic and acts as a detergent molecule with surfactant property. The milk also contains whey proteins with principle fractions of the b-lacto globulin, a-lactalbumin, bovine serum albumin and immunoglobulins. These molecules were found to be surface active with a superior solubility than caseins.28 Aminoacids have been suggested either as additives in peroral application or in the form of aminoacid salts to reduce gastrointestinal disorders arising due to piroxicam like NSAIDs. The surface active agents and amino acid content are expected to be the reason for increased permeation of the drug from the solid dispersion.29,30

Sunday, October 13, 2019

Body Art :: Social Issues, Tattooing

The number of people getting tattoos seems to be on the rise. According to the most recent Harris Poll, conducted in the summer of 2007, approximately 40% of Americans ages 25-40 have at least one tattoo, as compared to 3% 20 years ago (Hawkes, Senn, & Thorn, 2004). The increased popularity of the tattoo is apparent if you compare those findings to the 1936 Life magazine estimate that 10 million Americans, or approximately 6% of the population, had a tattoo (Swan, 2011). According to Kang and Jones (2007), tattooing is especially popular among teenagers and college students. At a stage when young people are seeking to assert their independence, tattoos may provide a way to ground a sense of self in a seemingly changing and insecure world. Tattooing has a long history; it was thought that tattooing was primary an ancient Egyptian practice dating from circa 2000 B.C. (Nadler, 1983). It was brought to the New World in 1769 by sailors returning from voyagers to the South Pacific (Post, 1968; Sanders, 1991). The practice of tattooing became more widespread and socially acceptable in the Western world after that time (Sanders, 1991). In ancient times tattooing was a projection of Jungian psychological elements, which was used be projected onto holy symbols, onto the self as a manifestations of self-expression coinciding with a decline in traditional religious adherence (Mercury, 2000). Piercing has almost as long of a history as tattooing. It was practiced by Egyptian pharaohs, Mayans, and Romans (Armstrong, 1996). Body piercing is sometimes studied along with tattooing, partly because people with tattoos often have piercings (Buhrich, 1983; Frederick & Bradley, 2000). For women, ear piercing has come to be viewed as a mainstream practice but piercing eyebrows, nose, cheeks, or other areas appears to symbolize one’s disaffection from society, much like tattooing (Sanders, 1988). Regarding piercings, 69.7% of women compared to 28.2% of men reported having piercings (Huxley & Grogan, 2005). The gender difference was significant. A way of being mischievous for a woman or going over the edge or developing a sexual identity is to have a piercing: navel, nipple, and nose (Saunders & Armstrong, 2005). The piercing can also draw attention to areas that the woman wants attention drawn to. Risquà ©-piercing may enhance the desire to use piercing for sexual attention . It may be that women may become pierced more for reasons of rebellion and men may become pierced more for reasons of self-identity (Caliendo, Armstrong, & Roberts, 2005).